Molagri's High-Science Bet: Can a YC War Chest Scale Deep-Tech in Toronto?

AI-generated image · Bay Street Wire
Founded by U of T PhDs, Molagri is leveraging AI protein design to fight pest resistance—but its struggle to find local funding highlights a gap in the Canadian VC landscape.
In a city often dominated by lightweight SaaS, Molagri is the kind of high-science, high-risk bet Toronto needs more of. As first reported by BetaKit, the startup is preparing for its next growth phase, raising the question of whether a Y Combinator 'war chest' is enough to scale deep-tech talent in a local ecosystem that sometimes shies away from the hard stuff.
**The Science of Evolutionary Pesticides** According to BetaKit, Molagri is tackling a fundamental problem in agriculture: the fact that pests evolve to resist pesticides every year. To counter this, founders Zaky Hassan and Min Jin—both PhD candidates from the University of Toronto who specialized in common cold coronaviruses—are developing pesticides that can 'evolve' alongside the pests.
Hassan told BetaKit that the company uses AI-driven advancements in protein design to synthesize targeted pesticides. Built on a non-infectious insect virus, the technology allows Molagri to 'whitelist' and 'blacklist' targets, enabling them to tweak formulations to stay ahead of resistance. Hassan likened the approach to a flu vaccine, noting that farmers shouldn't have to worry about which strain is present because the solution is handled in the back end.
**The Funding Gap** While the vision is ambitious, the path to funding it locally was not. BetaKit reports that Hassan and Jin initially sought Canadian investors to fund the concept, but were unsuccessful. Hassan attributed this lack of local support to the risk aversion of Canadian investors.
Instead, the duo raised $1 million USD (approximately $1.4 million CAD) in pre-seed capital from US-based deeptech VC Julian Capital and Y Combinator. This capital allowed the startup to secure lab space at the MaRS Discovery District and hire its first scientist.
**Scaling the Vision** Molagri is currently focusing its 'wedge product' on tree fruits and tree nuts due to an 'acute insecticide need,' which means much of the initial operational focus is on California. However, Hassan's long-term goal is to build the company in Canada.
Speaking with BetaKit, Hassan emphasized the importance of building bio companies in Toronto to strengthen the local ecosystem, citing the abundance of 'brilliant postdocs [and] grad students' as a primary reason why the city is a powerhouse for talent. As the founders prepare to pitch at Y Combinator’s Demo Day on Sept. 10, Hassan plans to use a forthcoming seed raise to bring more resources back to Toronto to hire additional scientists.
*Opinion: Molagri is exactly the type of moonshot that puts Toronto on the map for deep-tech. But if our local VCs continue to pass on these founders in favor of safer bets, we risk becoming a talent farm for US-based funds like Julian Capital rather than a hub for global bio-innovation.*

